Comparison of a normal aged brain (left) and the brain of a person with Alzheimer's (right). Characteristics that separate the two are pointed out.
Alzheimer's disease (AD) or simply Alzheimer's, is a neurodegenerative disease. This is a type of disease that started slowly and with time its impact became very completed. . It is the reason of 60% to 70% of dementia. Its symptom in earlier stage is difficulty in memorizing recent happenings. When the disease gets maturated, people suffer from the problems of language, disorientation mood swings, loss of motivation, not able to self-care, and behavioral. With the complexion of disease effect people loses their body function and ultimately resulted to death. Once people infected with this disease they usually got the time of three to nine years.
The exact cause of Alzheimer’s disease has poorly understood. It is said that around 70% of the risk are genetic. Other reason is assumed to head injuries, depression, and hypertension. In this disease plaques and tangles in the brain occur. Diagnosis of this disease is grounded on the history of the illness and cognitive testing. To identify the disease the examination of brain tissue is required for a definite diagnosis. Avoiding obesity can decrease the risk of AD however there is no medications or supplements that can decrease risk.
In recent time in the field of Alzheimer’s disease testing, Cardiff University has developed an important simple blood test to predict the Alzheimer's disease.
A group of academics of university of Cardiff, King's College of London and Oxford University made research in 292 people. Blood of 292 people collected and did research with the earliest signs of memory deficiency and observed a set of biomarkers (indicators of disease) that predicted whether or not a given person would develop Alzheimer's disease.
According to Paul Morgan, (Director, Cardiff University's Systems Immunity Research Institute) stated that “it is possible to predict whether or not a person with mild memory problems is most likely to progress Alzheimer's disease over the next few years. They hope to develop on this, a simple blood test that can predict the possibility of developing Alzheimer's disease in older people having mild and possibly innocent memory loss.
The study acquired blood samples from persons offering with very common symptoms of memory loss and measured a great number of proteins belonging to a part of the resistant system which is known to drive inflammation and has formerly been occupied in brain diseases. When the persons were re-assessed after one year it was found that around a quarter had progressed to Alzheimer's disease whereas three of the proteins measured in their blood showed substantial differences from the blood of members that did not go on to develop the disease.
Professor Morgan added: "Alzheimer's disease affects around 520,000 individuals in the UK and this number is continually growing as the population ages. As such it is important that we find new ways to identify the disease early, giving us a chance to investigate and initiate new treatments before permanent destruction is done.
Symptom of Alzheimer's disease
1. Memory loss that cause problem in daily life
Common symptom of Alzheimer's is loss in memory, people with this used to forget the recent activities that they have learn recently, they used to forget important dates , events , repeating of same thing again and again and need to remind memory aids.
2. Change in planning or solving problem
Some persons may feel changes in their capability to develop and follow a strategy or work with numbers. They may have trouble following a familiar recipe, tracking of monthly bills. And most importantly they could have difficulty in concentrating and take longer time to do those things that they do immediately earlier
3. Difficulty in completing familiar task at home, office or leisure
Persons with Alzheimer's frequently find it hard to complete daily tasks. Sometimes, he may have problem driving to a known location, handling a budget at work or memorizing the rules of a favorite game.
4. Confusion with time or place
Alzheimer's patients can lose track of dates, seasons and the passage of time. He could have trouble in understanding thing if it is not happen immediately. In some cases he could forget where they are or how they arrived there.
5. Understanding visual images and spatial relationship
Some people could have vision problem due to the Alzheimer’s. He may have difficulty in reading, judging distance and determining color or contrast,
6. Problems with words in speaking and writing
Persons with Alzheimer's may have trouble following or joining a conversation so he may try to stop in the middle of conversation. They may face problem in finding right words.
7. Misplacing things and losing the ability to repeat steps.
A person suffering from Alzheimer’s may put things in unusual places. They may lose things and be incapable to go back over their steps to find them again.
8. Decreased or poor judgment
Persons with Alzheimer's may experience problem in judgment or decision-making. He may use poor judgment when dealing with money, giving large amounts to telemarketers. He may pay less responsiveness to grooming or keeping yourself clean.
9. Withdrawal from work or social events
A person with Alzheimer's may use to remain far from their hobbies, social activities or sports. They may try to not mix with social activities because of the changes they have experienced.
10. Change in mood and personality
Alzheimer’s can grow change in mood and personality of the people. They can be confused, suspicious, depressed, fearful or anxious. They easily upset at home, at work, with friends or in places if they are not in their comfort zone.
If anyone notices any of these Warning Signs of Alzheimer's in yourself or someone you know, go and suggest him to consult with a doctor